Saturday, May 16, 2015

Corlux (same as Mifeprex) for Cushing syndrome 2007

Endo and Health News from 2007 / Cushing's Help and Support
...tumor on the pituitary gland at the base of the brain... This Topic on the Message Boards Washington Post August 14, 2007 CORLUX for the treatment of Cushing's Syndrome, orphan drug designation Corcept is still determining its... - Dec 20, 2008 - Relevance: 100.00%
Current Clinical Trials / Cushing's Help and Support
...Drug: C2L-OCT-01 PR, 10 or 20 mg; Drug: C2L-OCT-01 PR, 20 mg 53 Recruiting A Study of the Efficacy and Safety of CORLUX in the Treatment of Endogenous Cushing's Syndrome Condition: Cushing's Syndrome Intervention: Drug:... - Dec 20, 2008 - Relevance: 76.00%

My old treatment update draft as of Jan 2009

I have been taking Mifepristone again a second time in an independent investigational study approved by the FDA to control my recurrent meningioma since Feb 2005 and according to my documented six month MRIs at the University of Arizona MRI Imaging Center my low grade 2 brain tumor is still stable, no change in Jan 2009.
It took a full year from March 04 to Feb 05 to get all the legal paperwork approved by the FDA, the Institutional Review board at the U of AZ and the brand name product Mifepex distributed by Danco Inc in NYC which has increased the cost of my off label use of the medicine from $5 a day to $15 a day in the past three years.

David Dunlap, who I met online in the JHU m email list many years ago, generously sent me his dear Linda Dunlap's extra month of daily doses of Mifeprex instead of throwing it away, after she passed away in August of 2008. she had been taking it successfully to control her meningioma regrowth without any serious longterm side effects since 1987. She was truly a great lady who helped many other people during her lifetime and is sorely missed by her many dear friends in California and those who read her website.

In 2007 the FDA approved Mifepristone in an orphan drug brand name Corlux for Cushing disease symptoms. (caused by a pituitary adenoma or compression of the pituitary gland which is centrally located in the brain by an adjacent low grade tumor of any kind)

Please look up Cushing disease symptoms to compare to your own current symptoms which was named after Dr. Harvey Cushing, the same great neurosurgeon who discovered and named meningioma brain tumors many years ago.

I highly recommend the ABTA publications and support services to all brain tumor patients and their loved ones.

To my dear bt family online and all my Meningimates,

I had a good time in Florida at the ABTA conference in Tampa and just handed out the rest of the free ABTA literature (BT Primer handbook and BT Medical Dictionary) from the American Brain Tumor Association I picked up in Florida to the new members of our local monthly BT support group in Tucson at UMC/AZCC, now a Banner Hospital where I had my successful left lung tumor removal surgery for squamous cell carcinoma lung cancer last fall, September, 2014. (It was found early and there was no lymph node involvement.)

I think these ABTA publications are a very informative gift for many of our fine doctors who may not have had a chance to read them either. Topics include a dozen specific brain tumor types and various surgery, radiation and chemo treatment options, comprehensive brain tumor support services, fund raising events and volunteer opportunities everyone should be made aware of as soon as possible. For the past twenty years the in Chicago and the National Brain Tumor Society on both the east and west coast have been my GO TO non profit organizations for individual support, regional events and educational resources for the complex needs and advocacy issues of all brain tumor patients and their caregivers.

For example, the ABTA Meningioma brochure lists eight less invasive drug treatment options (not standard surgery and radiation therapy) that have been used with some success and/or are being further explored and investigated in recent years for meningiomas. Some of you might want to ask your doctors about these clinical trial and investigational drugs. Hydroxyurea, and progesterone receptor inhibitors like the Mifepristone I take, Somatostatin analogs, Targeted molecular agents, Epidermal growth factor inhibitors (EGFR), Platelet derived growth factor receptors (PDGFR), Vascular endothelial growth factor inhibitors (VEGF), and Immunotherapy/the use of biological agents to stimulate your immune system.

For more information and printed materials contact the ABTA Careline at 1-800-886-2282 or visit their website at